In a Berlin grappling with the effects of global warming and a reformed healthcare system that assigns treatment based on a "good conduct" point system, the Charité hospital faces unprecedented strain. Dr. Maral Safadi, a leading microbiologist, returns to the hospital alongside her wife, gynecologist Julia Kowalczyk. Maral confronts a mysterious, antibiotic-resistant bacterium linked to melting permafrost in Greenland. As the outbreak escalates, she endeavors to develop an innovative therapy, even resorting to self-experimentation to validate her findings.